SYNTHESIS OF SOME NON-PROTEIN AMINO ACIDS DERIVED FROM SPIROHYDANTOINS
SYNTHESIS OF SOME NON-PROTEIN AMINO ACIDS DERIVED FROM SPIROHYDANTOINS
DOI:
https://doi.org/10.46687/jsar.v10i1.204Keywords:
Synthesis, Non-protein Amino Acids, SpirohydantoinsAbstract
This article presents a synthesis of non-protein amino acids derived from 6- and 8- substituted cyclohexanespiro-5-hydantoins, spiro(adamantane-2',4'-imidazolidine)- 2,5-dione and 3',4'-dihydro-2H,2'H,5H-spiro[imidazolidine-4,1'-naphthalene]-2,5-dione. The target compounds were prepared by an alkaline hydrolysis of the corresponding spirohydantoins with barium hydroxide. The products obtained were characterized by physicochemical parameters, IR , 1H and 13C NMR spectral data.
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