SYNTHESIS OF SOME NON-PROTEIN AMINO ACIDS DERIVED FROM SPIROHYDANTOINS: SYNTHESIS OF SOME NON-PROTEIN AMINO ACIDS DERIVED FROM SPIROHYDANTOINS

Marin  Marinov; Emilia  Naydenova; Rumyana  Prodanova; Neyko  Stoyanov

doi:10.46687/jsar.v10i1.204

Authors

Marin N. Marinov DEPARTMENT OF GENERAL CHEMISTRY, FACULTY OF PLANT PROTECTION AND AGROECOLOGY, AGRICULTURAL UNIVERSITY – PLOVDIV
Emilia D. Naydenova DEPARTMENT OF ORGANIC CHEMISTRY, UNIVERSITY OF CHEMICAL TECHNOLOGY AND METALLURGY
Rumyana Y. Prodanova DEPARTMENT OF GENERAL CHEMISTRY, FACULTY OF PLANT PROTECTION AND AGROECOLOGY, AGRICULTURAL UNIVERSITY – PLOVDIV
Neyko M. Stoyanov DEPARTMENT OF CHEMISTRY AND CHEMICAL TECHNOLOGIES, “ANGEL KANCHEV” UNIVERSITY OF RUSE, RAZGRAD BRANCH

DOI:

https://doi.org/10.46687/jsar.v10i1.204

Keywords:

Synthesis, Non-protein Amino Acids, Spirohydantoins

Abstract

This article presents a synthesis of non-protein amino acids derived from 6- and 8- substituted cyclohexanespiro-5-hydantoins, spiro(adamantane-2',4'-imidazolidine)- 2,5-dione and 3',4'-dihydro-2H,2'H,5H-spiro[imidazolidine-4,1'-naphthalene]-2,5-dione. The target compounds were prepared by an alkaline hydrolysis of the corresponding spirohydantoins with barium hydroxide. The products obtained were characterized by physicochemical parameters, IR , 1H and 13C NMR spectral data.

Author Biographies

Marin N. Marinov, DEPARTMENT OF GENERAL CHEMISTRY, FACULTY OF PLANT PROTECTION AND AGROECOLOGY, AGRICULTURAL UNIVERSITY – PLOVDIV

DEPARTMENT OF GENERAL CHEMISTRY, FACULTY OF PLANT PROTECTION AND AGROECOLOGY, AGRICULTURAL UNIVERSITY – PLOVDIV

Emilia D. Naydenova, DEPARTMENT OF ORGANIC CHEMISTRY, UNIVERSITY OF CHEMICAL TECHNOLOGY AND METALLURGY

DEPARTMENT OF ORGANIC CHEMISTRY, UNIVERSITY OF CHEMICAL TECHNOLOGY AND METALLURGY

Rumyana Y. Prodanova, DEPARTMENT OF GENERAL CHEMISTRY, FACULTY OF PLANT PROTECTION AND AGROECOLOGY, AGRICULTURAL UNIVERSITY – PLOVDIV

DEPARTMENT OF GENERAL CHEMISTRY, FACULTY OF PLANT PROTECTION AND AGROECOLOGY, AGRICULTURAL UNIVERSITY – PLOVDIV

Neyko M. Stoyanov, DEPARTMENT OF CHEMISTRY AND CHEMICAL TECHNOLOGIES, “ANGEL KANCHEV” UNIVERSITY OF RUSE, RAZGRAD BRANCH

DEPARTMENT OF CHEMISTRY AND CHEMICAL TECHNOLOGIES, “ANGEL KANCHEV” UNIVERSITY OF RUSE, RAZGRAD BRANCH

SYNTHESIS OF SOME NON-PROTEIN AMINO ACIDS DERIVED FROM SPIROHYDANTOINS